Pofika 2030, mmodzi mwa anthu asanu aku America adzakhala ndi zaka 65.1 Pamene chiwerengero cha anthu aku US chikupitilira kukalamba, kufunikira kosankha chithandizo cha presbyopia kumafunikira.Odwala ambiri amayang'ana njira zina osati magalasi kuti awongolere masomphenya awo apakati komanso pafupi.Amafunikira chisankho chomwe chikugwirizana bwino ndi moyo wawo watsiku ndi tsiku ndipo sichiwonetsa kuti maso awo akukalamba.
Multifocal contact lens ndi njira yabwino yothetsera presbyopia, ndipo ndithudi si yatsopano.Komabe, akatswiri ena a maso akuyeserabe kugwiritsa ntchito magalasi olumikizana ndi ma multifocal pakuchita kwawo.ZOKHUDZANA NAZO: Chithandizo cha magalasi olumikizirana ndi kofunika kwambiri kuti tichotse ma coronavirus Kutengera chithandizochi sikuti kumangowonetsetsa kuti odwala ali ndi mwayi wopeza ukadaulo waposachedwa wa chisamaliro cha maso, komanso kumakulitsa kupambana kwa mchitidwewu potengera bizinesi.
1: Bzalani mbewu zambiri.Presbyopia ndi msika womwe ukukula.Anthu opitilira 120 miliyoni aku America ali ndi presbyopia, ndipo ambiri aiwo sadziwa kuti amatha kuvala magalasi olumikizana ndi ma multifocal.2
Odwala ena amapeza kuti magalasi opita patsogolo, ma bifocals, kapena magalasi owerengera okhawo ndi okhawo omwe angasankhe kuti awongolere pafupi ndi kuwonongeka kwa masomphenya komwe kumachitika chifukwa cha presbyopia.
Odwala ena adauzidwa kale kuti magalasi olumikizana ndi ma multifocal sali oyenera kwa iwo chifukwa cha zomwe adalemba kapena kukhalapo kwa astigmatism.Koma dziko la multifocal contact lens lasintha ndipo pali njira zambiri zomwe odwala angasankhe.Kafukufuku waposachedwapa wapeza kuti anthu 31 miliyoni amagula magalasi owerengera a OTC chaka chilichonse, nthawi zambiri m'masitolo akuluakulu kapena ku pharmacy.3
Monga osamalira maso oyambira, ma optometrists (OD) ali ndi kuthekera kodziwitsa odwala njira zonse zomwe zilipo kuti athe kuwona bwino ndikusintha moyo wawo.
Yambani powauza odwala kuti magalasi olumikizana ndi ma multifocal amatha kukhala njira yoyamba yowongolera masomphenya kapena kusankha kwanthawi yochepa, zosangalatsa, kapena kuvala kumapeto kwa sabata.Fotokozani momwe anthu olumikizana nawo amagwirira ntchito, momwe amagwirira ntchito, komanso momwe amalumikizirana ndi moyo watsiku ndi tsiku.Ngakhale odwala atasiya magalasi ambiri chaka chino, angafune kuganiziranso zomwe angasankhe mtsogolo.zokhudzana: Ofufuza akuyesa magalasi olumikizirana odzitchinjiriza a 3D
Ophthalmologists nthawi zambiri amalumikizana ndi odwala kunja kwa chipinda choyesera, zomwe zingawapatse mwayi wophunzitsa odwala za multifocal contact lens.
2: Tsatirani malangizo unsembe.Ndikofunika kutsatira malangizo oyenerera omwe amabwera ndi lens iliyonse.Izi ndizowona makamaka pamagalasi olumikizana ndi ma multifocal, popeza mitundu yosiyanasiyana imakhala ndi zone zowoneka bwino komanso njira zovala.Makampani nthawi zambiri amayang'ananso malingaliro awo okhudzana ndi ma lens pomwe ma lens ambiri amalumikizana ndi ogwiritsa ntchito odwala.Madokotala ambiri amapanga njira zawo zosinthira.Izi zitha kugwira ntchito kwakanthawi kochepa koma nthawi zambiri zimapangitsa kuti pakhale nthawi yowonjezereka ya mpando komanso chiwopsezo chochepa cha odwala omwe ali ndi magalasi olumikizana ndi ma multifocal.Ndikofunikira kuti nthawi ndi nthawi muziwunikanso zolemba zamagalasi omwe mumavala pafupipafupi.
Ndinaphunzira phunziroli zaka zambiri zapitazo pamene ndinayamba kuvala magalasi a Alcon Dailies Total 1 multifocal.Ndinagwiritsa ntchito njira yoyenerera yofanana ndi ma lens ena ambiri pamsika omwe amagwirizanitsa ma lens otsika / apakatikati / apamwamba otalikirapo kuti wodwalayo athe kuwonjezera (ADD).Njira yanga yoyenerera sinakwaniritse malingaliro oyenerera, zomwe zidapangitsa kuti pakhale nthawi yayitali yapampando, kuyendera ma lens angapo, komanso odwala omwe ali ndi masomphenya apakati.
Nditabwerera ku kalozera wokhazikitsa ndikutsata, zonse zidasintha.Pa lens yolumikizira iyi, onjezani +0.25 pakuwongolera kozungulira ndikugwiritsa ntchito mtengo wotsika kwambiri wa ADD kuti mugwirizane bwino.Kusintha kosavuta kumeneku kunabweretsa zotsatira zabwino pambuyo pa kuyesa kwa lens koyamba ndipo kunapangitsa kuti pakhale nthawi yochepetsera mpando komanso kukhutira kwa odwala.
3: Khazikitsani zoyembekeza.Tengani nthawi yokhazikitsa ziyembekezo zenizeni ndi zabwino.M'malo mofuna masomphenya abwino a 20/20 pafupi ndi kutali, masomphenya ogwirira ntchito pafupi ndi akutali angakhale mapeto oyenera.Wodwala aliyense ali ndi zosowa zosiyanasiyana zowonera, ndipo masomphenya a wodwala aliyense amasiyana kwambiri.Ndikofunikira kudziwitsa odwala kuti kupambana kwagona pakutha kugwiritsa ntchito magalasi pazochitika zawo zambiri zatsiku ndi tsiku.zokhudzana: Phunziro likuwonetsa Ogula Samvetsetsa Mozama Ma Lens Ndimalangizanso odwala kuti asafanizire masomphenya awo ndi magalasi olumikizana ndi magalasi ambiri ndi magalasi chifukwa ndi kufananitsa maapulo ndi malalanje.Kukhazikitsa zoyembekeza zomveka izi kumapangitsa wodwalayo kumvetsetsa kuti ndi bwino kusakhala wangwiro 20/20.Komabe, odwala ambiri amapeza 20/20 onse ali patali komanso pafupi ndi magalasi amakono a multifocal.
Mu 2021, McDonald et al.adapereka gulu la presbyopia, kugawa mkhalidwewo m'magulu ochepa, ocheperako, komanso ovuta.4 Njira yawo imayang'ana makamaka pakuyika presbyopia kudzera pakuwongolera masomphenya pafupi ndi zaka.M'dongosolo lawo, kuwongolera bwino kowoneka bwino kumayambira 20/25 mpaka 20/40 kwa presbyopia yofatsa, kuchokera 20/50 mpaka 20/80 ya presbyopia yodziyimira, komanso pamwamba 20/80 ya presbyopia yovuta.
Gulu ili la presbyopia ndiloyenera kwambiri ndipo limafotokoza chifukwa chake nthawi zina presbyopia mwa wodwala wazaka 53 akhoza kutchulidwa kuti ndi wofatsa, ndipo presbyopia mwa wodwala wazaka 38 akhoza kutchulidwa kuti ndi ochepa.Njira iyi ya presbyopia imandithandiza kusankha ma lens abwino kwambiri olumikizana nawo ndikukhazikitsa zomwe ndikuyembekezera kwa odwala anga.
4: Pezani njira zatsopano zothandizira adjuvant.Ngakhale ziyembekezo zolondola zitakhazikitsidwa ndikutsatiridwa koyenera, magalasi olumikizana ndi ma multifocal sangakhale njira yoyenera kwa wodwala aliyense.Njira imodzi yothetsera mavuto yomwe ndapeza kuti ndi yopambana ndiyo kugwiritsa ntchito Vuity (Allergan, 1.25% pilocarpine) ndi magalasi olumikizana ndi ma multifocal kwa odwala omwe sangathe kukwaniritsa tanthauzo lomwe akufuna pakatikati kapena pafupi.Vuity ndiye mankhwala oyamba ovomerezeka ndi FDA ochizira presbyopia mwa akulu.zokhudzana: Kulankhula ndi Presbyopia Contact Lens Loss Poyerekeza ndi pilocarpine, kukhathamiritsa kwa pilocarpine kwa 1.25% kuphatikiza ndiukadaulo wa pHast wovomerezeka kumapangitsa Vuity kukhala yosiyana komanso yothandiza kwambiri pakuwongolera zamankhwala a presbyopia.
Vuiti ndi cholinergic muscarinic agonist yokhala ndi njira ziwiri zochitira.Imayambitsa iris sphincter ndi ciliary yosalala minofu, motero imakulitsa kuya kwa munda ndikuwonjezera malo okhalamo.Mwa kuchepetsa wophunzira, monga mu pinhole Optics, masomphenya apafupi amakhala bwino.
Vuity anamaliza 2 parallel Phase 3 mayesero azachipatala (Gemini 1 [NCT03804268] ndi Gemini 2 [NCT03857542]) mwa omwe ali ndi zaka 40 mpaka 55 zaka zowoneka bwino pakati pa 20/40 ndi 20/100.Mayesero azachipatala awonetsa kuti mu myopia (kuwala kochepa) kunali kusintha kwa mizere ya 3, pomwe masomphenya akutali sanakhudze kuposa mzere umodzi (zilembo 5).
Pazithunzi, 9 mwa 10 omwe adachita nawo kafukufuku adachita bwino pafupi ndi masomphenya kuposa 20/40 pazithunzi.Mu kuwala kowala, gawo limodzi mwa magawo atatu a omwe adatenga nawo mbali adatha kukwaniritsa 20/20.Mayesero azachipatala awonetsanso kusintha kwa masomphenya apakati.Zotsatira zoyipa kwambiri ndi Vuiti zinali conjunctival hyperemia (5%) ndi mutu (15%).Muzochitika zanga, odwala omwe amamva kupweteka kwa mutu amanena kuti mutu ndi wochepa, wosakhalitsa, ndipo umachitika tsiku loyamba la kugwiritsa ntchito Vuity.
Vuiti imatengedwa kamodzi patsiku ndipo imayamba kuchita mkati mwa mphindi 15 mutatha kulowetsedwa.Odwala ambiri amanena kuti izi zimatha maola 6 mpaka 10.Mukamagwiritsa ntchito Vuity yokhala ndi ma lens, madontho amayenera kuyikidwa m'maso popanda magalasi olumikizana.Pambuyo pa mphindi 10, mandala amatha kulowetsedwa m'diso la wodwalayo.Vuiti ndi madontho a maso omwe mungagule ku pharmacy iliyonse.Ngakhale Vuity sinaphunzirepo kuphatikiza magalasi olumikizana ndi ma multifocal, ndapeza kuti nthawi zina njira yophatikizirayi imalola odwala omwe ali ndi magalasi olumikizana ndi ma multifocal kuti akwaniritse kusintha komwe akufunidwa pafupi ndi masomphenya.
Nthawi yotumiza: Sep-11-2022
