Ma lens amitundu iwiri a biocompatible plasma owongolera khungu

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Pakafukufuku waposachedwa wofalitsidwa mu nyuzipepala ya Scientific Reports, magalasi olumikizana amitundu iwiri komanso otanuka a plasmonic adapangidwa pogwiritsa ntchito polydimethylsiloxane (PDMS).
Kafukufuku: Ma lens amitundu iwiri a biocompatible plasma owongolera khungu. Ngongole ya zithunzi: Sergey Ryzhov/Shutterstock.com
Apa, mapangidwe otsika mtengo owongolera khungu lamtundu wobiriwira wobiriwira adapangidwa ndikuyesedwa kutengera nanolithography yofatsa.
Malingaliro amtundu wa munthu amachokera ku ma cell atatu ooneka ngati ma photoreceptor cell, aatali (L), apakati (M), ndi aafupi (S) cones, omwe ndi ofunikira kuti muwone mitundu yofiyira, yobiriwira, yabuluu, yokhala ndi chidwi chofikira 430. , 530 ndi 560 nm, motero.

filimu yamtundu wa lens
Colour blindness, yomwe imadziwikanso kuti color vision deficiency (CVD), ndi matenda amaso omwe amalepheretsa kuzindikira ndi kutanthauzira mitundu yosiyanasiyana ndi ma cell atatu a photoreceptor omwe amagwira ntchito mowona bwino ndipo amagwira ntchito molingana ndi mawonekedwe awo a spectral sensitivity maxima. kukhala constrictive kapena chibadwa, amayamba chifukwa cha imfa kapena chilema mu cone photoreceptor maselo.
1 nthawi zamakulitsidwe .© Roostaei, N. and Hamidi, SM (2022)
Dichroism imachitika pamene imodzi mwa mitundu itatu ya maselo a cone photoreceptor palibe;ndipo imatchulidwa kuti proteophthalmia (palibe ma photoreceptors a cone ofiira), deuteranopia (palibe ma photoreceptors obiriwira), kapena trichromatic Color blindness (kusowa kwa ma photoreceptors a blue cone).
Monochromaticity, mtundu wocheperako wakhungu wamitundu, umadziwika ndi kusakhalapo kwa mitundu iwiri ya ma cone photoreceptor cell.
Monochromatics mwina ndi colorblind kotheratu (colorblind) kapena ali ndi ma photoreceptors a blue cone. Mtundu wachitatu wa trichromacy wosadziwika umachitika ngati mtundu umodzi wa ma cell a cone photoreceptor sukugwira ntchito bwino.
Aberrant trichromacy imagawidwa mu mitundu itatu kutengera mtundu wa cone photoreceptor defect: deuteranomaly (defective green cone photoreceptors), protanomaly (defective red cone photoreceptors), ndi tritanomaly (defective blue cone photoreceptors) photoreceptor cell).
Ma protans (protanomaly ndi protanopia) ndi deutans (deuteranomaly ndi deuteranopia), omwe amadziwika kuti protanopia, ndi mitundu yodziwika bwino ya khungu.
Protanomaly, nsonga zowoneka bwino za maselo ofiira amtundu wa buluu zimasinthidwa ndi buluu, pamene mphamvu yowonjezereka ya maselo obiriwira a cone ndi ofiira.
Chithunzi 2. (a) Chithunzi chojambula chojambula chopangidwa ndi PDMS-based 2D plasmonic contact lens, ndi (b) chithunzi chenicheni cha 2D flexible plasmonic contact lens.© Roostaei, N. and Hamidi, SM (2022)
Ngakhale kuti pakhala pali ntchito yochuluka yothandiza popanga chithandizo chopanda nzeru cha khungu lakhungu potengera njira zingapo zachipatala za matendawa, kusintha kwakukulu kwa moyo kumakhalabe mtsutso wowonekera. makompyuta ndi zida zam'manja ndi mitu yomwe idakambidwa mu kafukufuku wam'mbuyomu.
Magalasi okhala ndi zosefera zamitundu adafufuzidwa bwino ndipo akuwoneka kuti akupezeka kwambiri pochiza CVD.
Ngakhale kuti magalasiwa akuyenda bwino pakuwonjezeka kwa maonekedwe a mtundu kwa anthu akhungu, ali ndi zovuta monga mtengo wapamwamba, kulemera kwakukulu ndi kuchuluka kwake, komanso kusowa kophatikizana ndi magalasi ena owongolera.
Pakuwongolera CVD, magalasi olumikizana opangidwa pogwiritsa ntchito utoto wamankhwala, ma plasmonic metasurfaces, ndi ma plasmonic nanoscale particles adafufuzidwa posachedwa.
Komabe, magalasi olumikizana awa amakumana ndi zopinga zambiri, kuphatikiza kusowa kwa biocompatibility, kugwiritsa ntchito pang'ono, kusakhazikika bwino, kukwera mtengo, ndi njira zovuta kupanga.
Ntchito yomwe ilipo pano ikupereka magalasi olumikizana amitundu iwiri komanso zotanuka za plasmonic zochokera ku polydimethylsiloxane (PDMS) kuti akonze khungu lamtundu, ndikugogomezera mwapadera khungu lodziwika bwino la mtundu, deuterochromatic anomaly (red-green) khungu.
PDMS ndi biocompatible, flexible and transparent polima yomwe ingagwiritsidwe ntchito kupanga ma lens.Chinthu chopanda vuto komanso chogwirizana ndi biocompatible chapeza ntchito zosiyanasiyana m'makampani a zamoyo, zamankhwala ndi mankhwala.
Chithunzi 3. Chithunzi cha PDMS-based PDMS-based 2D plasmonic contact lens.© Roostaei, N. and Hamidi, SM (2022)
Mu ntchitoyi, ma lens a 2D biocompatible ndi elastic plasmonic opangidwa ndi PDMS, omwe ndi otsika mtengo komanso osavuta kupanga, adapangidwa pogwiritsa ntchito njira yofatsa ya nanoscale lithography, ndipo kuwongolera kwa deuteron kunayesedwa.
Magalasi amapangidwa kuchokera ku PDMS, hypoallergenic, yosakhala yowopsa, yotanuka komanso yowonekera polima. Izi plasmonic kukhudzana mandala, zochokera chodabwitsa cha plasmonic pamwamba lattice resonance (SLR), angagwiritsidwe ntchito ngati kwambiri mtundu fyuluta kukonza deuteron anomalies.
Ma lens omwe akufunsidwawo ali ndi zinthu zabwino monga kukhazikika, kukhazikika kwachilengedwe komanso kukhazikika, zomwe zimawapangitsa kukhala oyenera kuwongolera khungu.
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filimu yamtundu wa lens
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